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The generation and analysis of genetically modified mice, including transgenic and knockout animals, is an essential technology for cancer research. The Genetically Modified Mouse Models Shared Resource (GMMMSR) makes these powerful technologies available to all Cancer Center members and others.
Services include:
Jianwen Que, MD, Ph.D, Director
Chyuan-Sheng (Victor) Lin, Ph.D., Manager
Hours | Location |
Monday - Friday 10 am-4 pm |
Irving Cancer Research Center |
Name | Role | Phone | Location | |
---|---|---|---|---|
Jianwen Que, MD, PhD. |
Director
|
212-305-5961
|
jq2240@cumc.columbia.edu
|
|
Chyuan-Sheng (Victor) Lin, PhD. |
Manager
|
212-851-4716
|
CSL5@CUMC.COLUMBIA.EDU
|
1130 St. Nicholas Avenue ICRC 604, NY, NY 10032
|
Services & Rates |
► Services (18) | |||
Name | Description | Price | |
---|---|---|---|
14. BAC Injection (B6CBAF1) | Inquire | ||
15. BAC Injection (C57BL/6J) | Inquire | ||
3. Full CRISPR Service (C57BL/6J or B6CBAF1), HDR< 1kb, 2 founders guaranteed |
This full CRISPR gene editing service is a complete service offered by GMMMSR to generate a CRISPR-edited mouse line. Client provides the information about this mouse line and GMMMSR will design the approach and create this mouse line in 12 months. |
Inquire | |
1. CRISPR Injection (B6CBAF1), 10 pups guaranteed, no guarantee on editing | Inquire | ||
2. CRISPR Injection (C57BL/6J), 10 pups guaranteed, no guarantee on editing | Inquire | ||
8. Blastocyst Injection (each targeted ES clone) | Inquire | ||
9. Pronuclear Injection (B6CBAF1) | Inquire | ||
10. Pronuclear Injection (C57BL/6J) | Inquire | ||
4. ES Cell Electroporation | Inquire | ||
5. Expansion of targeted ES cells for first clone | Inquire | ||
6. Expansion of additional targeted clones for the same experiment | Inquire | ||
7. Thawing of targeted ES clones for blastocyst injection | Inquire | ||
11. ES Cell Derivation (setup charge) | Inquire | ||
12. ES Cell Derivation (Per ES Cell Line) | Inquire | ||
13. BAC Purification | Inquire | ||
16. Full Gene Targeting (129B6 hybrid ES cell) | Inquire | ||
17. Full Gene Targeting (C57BL/6 ES cell) | Inquire | ||
Other | Inquire |