High Throughput Screening (Systems Biology)

Overview of Services

The Columbia Genome Center provides high-quality molecular screening services for investigators throughout the Columbia University research community. 


Our high-throughput screening facility operates as a collaborative resource center. Our mission is to support both basic and translational biomedical research by designing, optimizing, and running high-throughput assays that deliver answers to questions of scientific interest.


Our staff is highly experienced in a wide range of technical applications for both generating and analyzing data. We work closely with our research partners to develop solutions that help you to achieve your experimental goals. As a participant in the Columbia University Department of Systems Biology, we also facilitate access to faculty with special expertise in a variety of related disciplines, including bioinformatics and advanced data analysis, as well as medicinal chemistry and chemical probe synthesis.


Please contact us to learn how the Columbia Genome Center can assist you in your research project.


High-throughput screening

  • High-throughput assay design, optimization, and implementation
  • Robotics and automated liquid handling
  • Access to curated small molecule, siRNA, and cDNA screening libraries
  • High-content automated image analysis
  • Multi-label plate detection
  • Integration of next-generation sequencing, small molecule synthesis, and organic chemistry



Charles Karan

Scientific Director

(212) 851-4862



Location and hours of operation

Hours Location

9 AM to 5 PM       

Russ Berrie Medical Science Pavilion 510 
1150 St. Nicholas Avenue 
New York, NY 10032

Links and Resources

  1. Columbia University - High Throughoutput Screening


Name Role Phone Email Location
Chuck Karan